Cyclobenzaprine Drug Lookup Pediatric Care Online American Academy of Pediatrics

The efficacy of FLEXERIL 5 mg was demonstrated in two seven-day, double-blind, controlled clinical trials enrolling 1405 patients. One study compared FLEXERIL 5 mg and 10 mg t.i.d. to placebo; and a second study compared FLEXERIL 5 mg and 2.5 mg t.i.d. to placebo. Primary endpoints for both trials were determined by patient-generated data and included global impression of change, medication helpfulness, and relief from starting backache. Each endpoint consisted of a score on a 5-point rating scale (from 0 or worst outcome to 4 or best outcome). The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly). The elderly may also be more at risk for CNS adverse events such as hallucinations and confusion, cardiac events resulting in falls or other sequelae, drug-drug and drug-disease interactions.

I can easily see how someone might become addicted to it though. Flexeril is a medication belonging to a class of skeletal muscle relaxants used to treat muscle spasms. These spasms may be induced by significant injuries of the musculoskeletal system or even due to usual physiological activities. Other brands apart from Flexeril are Amrix and Fexmid.

Cyclobenzaprine: Side Effects, dosage, uses, and more – Medical News Today

Cyclobenzaprine: Side Effects, dosage, uses, and more.

Posted: Fri, 22 May 2020 13:31:24 GMT [source]

It is a very powerful muscle relaxer, and it works quite well. It occurred to me that it might work even better if I used a little more than I normally would. I waited until I had a couple of days when I would be at home, by myself.

Adverse Effects

Cyclobenzaprine may enhance the effects of other central nervous system depressants, such as alcohol, barbiturates, benzodiazepines and narcotics. According to the DEA, abusers often combine cyclobenzaprine with these depressants to produce or enhance psychoactive effects. Though it is not a controlled substance, the DEA has recorded anecdotal reports of use to induce euphoria and relaxation. Cyclobenzaprine is a skeletal muscle relaxant that works by increasing the release of the chemical norepinephrine from central nervous structures in the brain, Patel said. Overtaking Flexeril, even in the daily recommended dose, can lead to uncomfortable side effects such as dry mouth, headaches, drowsiness, fatigue, and stomach pain. Abrupt cessation of treatment after prolonged administration rarely may produce nausea, headache, and malaise.

Getting high on Flexeril is kind of like being on a vacation.
Less common issues include central nervous depression.
If you notice other effects not listed above, contact your doctor or pharmacist.
Other common Flexeril side effects include nausea, dry mouth, and dizziness.
They belong to two different drug classes – muscle relaxant and benzodiazepine, respectively.

A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Flexeril, the brand name for cyclobenzaprine, is a muscle relaxant prescribed for mild to moderate muscle pain relief. It is prescribed in different doses depending on the type of muscle pain and how severe it is.

More on Flexeril

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs.

It produces a relaxing effect that one might consider a Flexeril high. If the dosage is tampered with, that will end up causing greater cyclobenzaprine high. A Flexeril high is really only possible when the medication is abused or when the patient first takes it. Some users, however, have If someone takes more than the prescription suggests, the Flexeril high can include an altered state of mind.

Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling. It’s not considered a dangerous method of getting rid of specific muscular pain. It is given to patients who are more likely to abuse opiate pain killers and is considered less risky for abuse and addiction. Cyclobenzaprine’s plasma concentrations average 40% higher in the elderly, making these patients more at risk of the drug’s harmful effects. The drug is also eliminated more slowly in this age group.

OVERDOSE

It’s not advised to drink alcohol at all while they’re being treated with Flexeril. People that combine Flexeril and alcohol also may not think properly and are more susceptible to making bad choices. Operating a vehicle while intoxicated, walking through a bad part of town, and other risks to physical harm may end up being more likely when abusing Flexeril and alcohol.

Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of FLEXERIL for periods longer than two or three weeks is not recommended. Eight double-blind controlled clinical studies were performed in 642 patients comparing FLEXERIL 10 mg, diazepam, and placebo. Muscle spasm, local pain and tenderness, limitation of motion, and restriction flexeril kidney in activities of daily living were evaluated. In three of these studies there was a significantly greater improvement with FLEXERIL than with diazepam, while in the other studies the improvement following both treatments was comparable. In patients with CNS depression, early intubation is advised because of the potential for abrupt deterioration.